GenePage for the dfp gene of Escherichia coli K-12

Primary Gene Name: dfp
EcoGene Accession Number: EG10004
K-12 Gene Accession Number: ECK3629
MG1655 Gene Identifier: b3639
Gene Name Mnemonic: DNA synthesis FlavoProtein
Alternate Gene Symbols: coaBC
Description: Coenzyme A biosynthesis, bifunctional enzyme; phosphopantothenoylcysteine decarboxylase (N) and phosphopantothenoylcysteine synthase (C)
  # bp Upstream # bp Downstream
Verified Start MW: 43438.14 ---------406 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3812731
Left Intergenic Region

Name: yicR_dfp

Length: 171 bp gap

Orientation: Divergent

Left_end: 3812560

Right_end: 3812730

Centisome: 82.14

Genomic Address
Clockwise
Minute or Centisome (%) = 82.14
Right End: 3813951
Right Intergenic Region

Name: dfp_dut

Length: 20 bp overlap

Orientation: Codirectional+

Left_end: 3813932

Right_end: 3813951

Centisome: 82.17

Dfp was originally identified as a flavoprotein affecting DNA synthesis and pantothenate metabolism. The N-terminal domain of Dfp catalyzes the decarboxylation of (R)-4'-phospho-N-pantothenoylcysteine to 4'-phosphopantetheine.

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BamHI EcoRI HindIII