GenePage for the acrD gene of Escherichia coli K-12

Primary Gene Name: acrD
EcoGene Accession Number: EG10014
K-12 Gene Accession Number: ECK2465
MG1655 Gene Identifier: b2470
Gene Name Mnemonic: Acridine
Alternate Gene Symbols: yffA
Description: Aminoglycoside efflux pump; RND-type transporter
  # bp Upstream # bp Downstream
MW: 113047.34 ---------1037 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2587595
Left Intergenic Region

Name: narQ_acrD

Length: 163 bp gap

Orientation: Codirectional+

Left_end: 2587432

Right_end: 2587594

Centisome: 55.74

Genomic Address
Clockwise
Minute or Centisome (%) = 55.75
Right End: 2590708
Right Intergenic Region

Name: acrD_ypfM

Length: 98 bp gap

Orientation: Convergent

Left_end: 2590709

Right_end: 2590806

Centisome: 55.81

An acrD mutation confers increased sensitivity to aminoglycosides. acrD is paralogous to acrB. EvgAS regulon.

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BamHI EcoRI HindIII