GenePage for the csrD gene of Escherichia coli K-12

Primary Gene Name: csrD
EcoGene Accession Number: EG10018
K-12 Gene Accession Number: ECK3240
MG1655 Gene Identifier: b3252
Gene Name Mnemonic: Carbon storage regulator
Alternate Gene Symbols: yhdA
Description: Targeting factor for csrBC sRNA degradation by RNase E; degenerate GGDEF/EAL protein; carbon flux regulator; indirectly affects CsrA function
  # bp Upstream # bp Downstream
MW: 73339.24 ---------646 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3401392
Left Intergenic Region

Name: mreB_csrD

Length: 304 bp gap

Orientation: Codirectional-

Left_end: 3401088

Right_end: 3401391

Centisome: 73.27

Genomic Address
Counterclockwise
Minute or Centisome (%) = 73.28
Right End: 3403332
Right Intergenic Region

Name: csrD_acuI

Length: 151 bp gap

Orientation: Divergent

Left_end: 3403333

Right_end: 3403483

Centisome: 73.32

In its c-di-GMP domains CsrD has HRSDF instead of GGDEF and ELM instead of EAL and does not appear to have either diguanylate cyclase or cyclic-di-GMP phosphodiesterase activities and the role of CsrD in csrB/C destabilization does not involve cyclic-di-GMP metabolism (Suzuki, 2006). There is a very low level of CsrD expression and CsrD may work at substoichiometric concentrations (Suzuki, 2006). False positive lipoprotein prediction, Cys not conserved.

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BamHI EcoRI HindIII