GenePage for the cysQ gene of Escherichia coli K-12

Primary Gene Name: cysQ
EcoGene Accession Number: EG10043
K-12 Gene Accession Number: ECK4210
MG1655 Gene Identifier: b4214
Gene Name Mnemonic: Cysteine
Alternate Gene Symbols: amt; amtA
Description: 3'(2'),5'-bisphosphate nucleotidase; converts pAp to AMP; lithium- and calcium-inhbited; putative PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase
  # bp Upstream # bp Downstream
MW: 27175.86 ---------246 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4436755
Left Intergenic Region

Name: cpdB_cysQ

Length: 189 bp gap

Orientation: Divergent

Left_end: 4436566

Right_end: 4436754

Centisome: 95.58

Genomic Address
Clockwise
Minute or Centisome (%) = 95.59
Right End: 4437495
Right Intergenic Region

Name: cysQ_ytfI

Length: 211 bp gap

Orientation: Codirectional+

Left_end: 4437496

Right_end: 4437706

Centisome: 95.60

CysQ is a main target of lithium toxicity in vivo. CysQ (AmtA) was originally thought to be involved in ammonium transport. CysQ may be part of a futile sulfur cycle with APS kinase CysC. CysQ is also known as 3'-phosphoadenosine 5'-phosphate (pAp) phosphatase. 6/78 CysQ peptide masses from MS analysis confirm this start codon and indicate that the initial Met is not removed (Maillet, 2007).

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII