GenePage for the birA gene of Escherichia coli K-12

Primary Gene Name: birA
EcoGene Accession Number: EG10123
K-12 Gene Accession Number: ECK3965
MG1655 Gene Identifier: b3973
Gene Name Mnemonic: Biotin retention
Alternate Gene Symbols: bioR; dhbB
Description: Bifunctional biotin protein ligase, biotin operon repressor; biotin-[acetyl-CoA carboxylase] holoenzyme synthase; monomeric
  # bp Upstream # bp Downstream
MW: 35312.00 ---------321 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4173082
Left Intergenic Region

Name: murB_birA

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 4173082

Right_end: 4173085

Centisome: 89.91

Genomic Address
Clockwise
Minute or Centisome (%) = 89.91
Right End: 4174047
Right Intergenic Region

Name: birA_coaA

Length: 28 bp gap

Orientation: Convergent

Left_end: 4174048

Right_end: 4174075

Centisome: 89.93

Biotinyl-5'-AMP is the co-repressor and is also synthesized by BirA (Cronan, 1988). BirA biotinylates AccB on K122. The biotin operon is regulated by the rate of protein biotination (Cronan, 1989).

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII