GenePage for the btuE gene of Escherichia coli K-12

Primary Gene Name: btuE
EcoGene Accession Number: EG10129
K-12 Gene Accession Number: ECK1708
MG1655 Gene Identifier: b1710
Gene Name Mnemonic: B12 uptake
Alternate Gene Symbols: None
Description: Glutathione peroxidase; non-specific peroxidase activity
  # bp Upstream # bp Downstream
MW: 20469.56 ---------183 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1793558
Left Intergenic Region

Name: btuD_btuE

Length: 1 bp overlap

Orientation: Codirectional-

Left_end: 1793558

Right_end: 1793558

Centisome: 38.64

Genomic Address
Counterclockwise
Minute or Centisome (%) = 38.64
Right End: 1794109
Right Intergenic Region

Name: btuE_btuC

Length: 62 bp gap

Orientation: Codirectional-

Left_end: 1794110

Right_end: 1794171

Centisome: 38.65

BtuE uses GSH, TrxA or TrxC as reducing agents in vitro; lipid peroxides could be the physiologically-relevant substrates for BtuE (Arenas, 2010). BtuE is induced by oxidative stress (Arenas, 2010). BtuE may be periplasmic but has no signal peptide; a periplasmic location for BtuE also seems unlikely in light of its use of Trx and Grx cytoplasmic proteins as reducing agents. Glutathione peroxidase family. Non-essential for vitamin B12 transport.

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BamHI EcoRI HindIII