GenePage for the fimC gene of Escherichia coli K-12

Primary Gene Name: fimC
EcoGene Accession Number: EG10310
K-12 Gene Accession Number: ECK4307
MG1655 Gene Identifier: b4316
Gene Name Mnemonic: Fimbriae
Alternate Gene Symbols: None
Description: Periplasmic chaperone for type 1 fimbriae; FimCD chaperone-usher transport
  # bp Upstream # bp Downstream
Verified Start MW: 26688.90 ---------241 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4544304
Left Intergenic Region

Name: fimI_fimC

Length: 36 bp gap

Orientation: Codirectional+

Left_end: 4544268

Right_end: 4544303

Centisome: 97.90

Genomic Address
Clockwise
Minute or Centisome (%) = 97.90
Right End: 4545029
Right Intergenic Region

Name: fimC_fimD

Length: 66 bp gap

Orientation: Codirectional+

Left_end: 4545030

Right_end: 4545095

Centisome: 97.92

The crystal structure of the pilus elongation complex in which the tip complex assembly composed of FimC, FimF, FimG and FimH passes through the usher porin FimD has been determined (Geibel, 2013). FimC has Ig-like domains: pfam PF00345 aligns to N-terminal residues 37-157, and pfam PF02753 aligns to C-terminal residues 161-237. The first 36 aa of FimC are a type I signal peptide.

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BamHI EcoRI HindIII