GenePage for the fur gene of Escherichia coli K-12

Primary Gene Name: fur
EcoGene Accession Number: EG10359
K-12 Gene Accession Number: ECK0671
MG1655 Gene Identifier: b0683
Gene Name Mnemonic: Ferric uptake regulation
Alternate Gene Symbols: None
Description: Ferric iron uptake global transcriptional repressor; Fe(2)-responsive; zinc metalloprotein
  # bp Upstream # bp Downstream
Verified Start MW: 16794.85 ---------148 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 710200
Left Intergenic Region

Name: chiQ_fur

Length: 83 bp gap

Orientation: Convergent

Left_end: 710117

Right_end: 710199

Centisome: 15.30

Genomic Address
Counterclockwise
Minute or Centisome (%) = 15.30
Right End: 710646
Right Intergenic Region

Name: fur_uof

Length: 8 bp overlap

Orientation: Codirectional-

Left_end: 710639

Right_end: 710646

Centisome: 15.31

Fur translation is coupled to the translation of the upstream leader peptide Uof; Uof translation is inhibited by the antisense sRNA ryhB; Uof translation opens up a hairpin that blocks Fur translation (Vecerek, 2007). Amino acid composition analysis indicates that the first Met is missing from the mature Fur protein (Wee, 1988). Binds TrxA (Kumar, 2004).

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BamHI EcoRI HindIII