GenePage for the hupA gene of Escherichia coli K-12

Primary Gene Name: hupA
EcoGene Accession Number: EG10466
K-12 Gene Accession Number: ECK3992
MG1655 Gene Identifier: b4000
Gene Name Mnemonic: HU protein
Alternate Gene Symbols: None
Description: Histone-like protein HU-alpha, HU-2
  # bp Upstream # bp Downstream
Verified Start MW: 9534.98 ---------90 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4200281
Left Intergenic Region

Name: yjaG_hupA

Length: 186 bp gap

Orientation: Codirectional+

Left_end: 4200095

Right_end: 4200280

Centisome: 90.49

Genomic Address
Clockwise
Minute or Centisome (%) = 90.49
Right End: 4200553
Right Intergenic Region

Name: hupA_yjaH

Length: 12 bp gap

Orientation: Codirectional+

Left_end: 4200554

Right_end: 4200565

Centisome: 90.50

HU concentration in the cell determines the mechanical effect; flexible bends responsible for compaction occur at concentrations <100nM, while increased concentrations result in the formation of a rigid nucleoprotein filament and no significant concentration. Mutant HU alters structure and function of the chromosome. HT_Cmplx32_Mem: CspC+Hns+HupA.

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BamHI EcoRI HindIII