GenePage for the oppA gene of Escherichia coli K-12

Primary Gene Name: oppA
EcoGene Accession Number: EG10674
K-12 Gene Accession Number: ECK1237
MG1655 Gene Identifier: b1243
Gene Name Mnemonic: Oligopeptide permease
Alternate Gene Symbols: None
Description: Oligopeptide ABC transporter periplasmic binding protein
  # bp Upstream # bp Downstream
Verified Start MW: 60898.93 ---------543 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1301182
Left Intergenic Region

Name: insH21_oppA

Length: 634 bp gap

Orientation: Codirectional+

Left_end: 1300548

Right_end: 1301181

Centisome: 28.02

Genomic Address
Clockwise
Minute or Centisome (%) = 28.03
Right End: 1302813
Right Intergenic Region

Name: oppA_oppB

Length: 85 bp gap

Orientation: Codirectional+

Left_end: 1302814

Right_end: 1302898

Centisome: 28.07

OppA binds oligopeptides from two to five amino acids long and has a preference for basic peptides, especially lysine-containing peptides (Klepsch, 2011). Polyamine modulon (Igarashi, 2006). Spermidine binds to oppA mRNA and stimulates OppA protein synthesis initiation (Igarashi, 1997; Igarashi, 2000; Higashi, 2008). After four hours of Zn(II) stress, OppA protein levels decreased (Easton, 2006).

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BamHI EcoRI HindIII