GenePage for the purE gene of Escherichia coli K-12

Primary Gene Name: purE
EcoGene Accession Number: EG10793
K-12 Gene Accession Number: ECK0516
MG1655 Gene Identifier: b0523
Gene Name Mnemonic: Purine
Alternate Gene Symbols: ade(f); ade3; Pur2
Description: N5-carboxyaminoimidazole ribonucleotide (N-CAIR) mutase; purine synthesis
  # bp Upstream # bp Downstream
Verified Start MW: 17780.32 ---------169 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 552591
Left Intergenic Region

Name: purK_purE

Length: 4 bp overlap

Orientation: Codirectional-

Left_end: 552591

Right_end: 552594

Centisome: 11.91

Genomic Address
Counterclockwise
Minute or Centisome (%) = 11.91
Right End: 553100
Right Intergenic Region

Name: purE_lpxH

Length: 117 bp gap

Orientation: Codirectional-

Left_end: 553101

Right_end: 553217

Centisome: 11.92

PurE was previously thought to be the catalytic subunit of phosphoribosylaminoimidazole carboxylase, with ATPase subunit PurK (Tiedeman, 1989). PurE is a separate N-CAIR mutase (Mueller, 1994; Meyer, 1999).

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BamHI EcoRI HindIII