GenePage for the secE gene of Escherichia coli K-12

Primary Gene Name: secE
EcoGene Accession Number: EG10939
K-12 Gene Accession Number: ECK3972
MG1655 Gene Identifier: b3981
Gene Name Mnemonic: Secretory
Alternate Gene Symbols: mbrC; prlG
Description: SecYEG inner membrane translocon core subunit; preprotein translocase secAYEG subunit; core translocon secYE subunit
  # bp Upstream # bp Downstream
MW: 13643.41 ---------127 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4177358
Left Intergenic Region

Name: tufB_secE

Length: 229 bp gap

Orientation: Codirectional+

Left_end: 4177129

Right_end: 4177357

Centisome: 89.99

Genomic Address
Clockwise
Minute or Centisome (%) = 90.00
Right End: 4177741
Right Intergenic Region

Name: secE_nusG

Length: 1 bp gap

Orientation: Codirectional+

Left_end: 4177742

Right_end: 4177742

Centisome: 90.01

SecYEG complex interacts with SecDFyajC to form a hexameric holocomplex. mbrC17 is a point mutation 23 nt before secE that increases secE and nusG expression, resulting in a suppression of camphor resistance by increasing cellular DNA content (Trun, 1991; Estevenon, 1997).

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BamHI EcoRI HindIII