GenePage for the thrA gene of Escherichia coli K-12

Primary Gene Name: thrA
EcoGene Accession Number: EG10998
K-12 Gene Accession Number: ECK0002
MG1655 Gene Identifier: b0002
Gene Name Mnemonic: Threonine
Alternate Gene Symbols: Hs; thrA1; thrA2; thrD
Description: Bifunctional aspartokinase/homoserine dehydrogenase 1; threonine-sensitive
  # bp Upstream # bp Downstream
Verified Start MW: 89120.24 ---------820 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 337
Left Intergenic Region

Name: thrL_thrA

Length: 81 bp gap

Orientation: Codirectional+

Left_end: 256

Right_end: 336

Centisome: 0.01

Genomic Address
Clockwise
Minute or Centisome (%) = 0.01
Right End: 2799
Right Intergenic Region

Name: thrA_thrB

Length: 1 bp gap

Orientation: Codirectional+

Left_end: 2800

Right_end: 2800

Centisome: 0.06

L-serine is a competitive inhibitor of both ThrA activities and L-threonine is an allosteric effector (Wright, 1977; Costrejean, 1977; Broglie, 1983).

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BamHI EcoRI HindIII