GenePage for the tolA gene of Escherichia coli K-12

Primary Gene Name: tolA
EcoGene Accession Number: EG11007
K-12 Gene Accession Number: ECK0728
MG1655 Gene Identifier: b0739
Gene Name Mnemonic: Tolerance
Alternate Gene Symbols: cim; excC; lky
Description: Tolerance to group A colicins, single-stranded filamentous DNA phage; required for OM integrity; membrane protein; bacteriocin tolerant
  # bp Upstream # bp Downstream
MW: 43156.63 ---------421 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 776342
Left Intergenic Region

Name: tolR_tolA

Length: 64 bp gap

Orientation: Codirectional+

Left_end: 776278

Right_end: 776341

Centisome: 16.72

Genomic Address
Clockwise
Minute or Centisome (%) = 16.73
Right End: 777607
Right Intergenic Region

Name: tolA_tolB

Length: 132 bp gap

Orientation: Codirectional+

Left_end: 777608

Right_end: 777739

Centisome: 16.75

Cell envelope integrity is stabilized by the Tol-Pal system linking inner and outer membranes. Mutants have elevated OM vesiculation (McBroom, 2006).

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BamHI EcoRI HindIII