GenePage for the topA gene of Escherichia coli K-12

Primary Gene Name: topA
EcoGene Accession Number: EG11013
K-12 Gene Accession Number: ECK1268
MG1655 Gene Identifier: b1274
Gene Name Mnemonic: Topoisomerase
Alternate Gene Symbols: asuA?; supX
Description: Topoisomerase I; omega protein
  # bp Upstream # bp Downstream
Verified Start MW: 97349.76 ---------865 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1331048
Left Intergenic Region

Name: yciN_topA

Length: 379 bp gap

Orientation: Divergent

Left_end: 1330669

Right_end: 1331047

Centisome: 28.67

Genomic Address
Clockwise
Minute or Centisome (%) = 28.68
Right End: 1333645
Right Intergenic Region

Name: topA_cysB

Length: 209 bp gap

Orientation: Codirectional+

Left_end: 1333646

Right_end: 1333854

Centisome: 28.73

Type I topoisomerase TopA relaxes DNA supercoils by nicking.

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BamHI EcoRI HindIII