GenePage for the ispH gene of Escherichia coli K-12

Primary Gene Name: ispH
EcoGene Accession Number: EG11081
K-12 Gene Accession Number: ECK0030
MG1655 Gene Identifier: b0029
Gene Name Mnemonic: Isoprenoid
Alternate Gene Symbols: lytB; yaaE
Description: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; last, branched, step of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) synthesis from 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate; alternative nonmevalonate (DXP) pathway for terp
  # bp Upstream # bp Downstream
MW: 34774.56 ---------316 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 26277
Left Intergenic Region

Name: fkpB_ispH

Length: 1 bp gap

Orientation: Codirectional+

Left_end: 26276

Right_end: 26276

Centisome: 0.57

Genomic Address
Clockwise
Minute or Centisome (%) = 0.57
Right End: 27227
Right Intergenic Region

Name: ispH_rihC

Length: 65 bp gap

Orientation: Codirectional+

Left_end: 27228

Right_end: 27292

Centisome: 0.59

The ispH gene is essential. IspH contains a [4Fe-4S] cluster. IspH affects penicillin tolerance and the stringent response. 2/42 IspH(LytB) peptide masses from MS analysis confirm this start codon and indicate that the initial Met is not removed (Maillet, 2007).

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII