GenePage for the relE gene of Escherichia coli K-12

Primary Gene Name: relE
EcoGene Accession Number: EG11131
K-12 Gene Accession Number: ECK1557
MG1655 Gene Identifier: b1563
Gene Name Mnemonic: Relaxed
Alternate Gene Symbols: None
Description: Sequence-specific mRNA endoribonuclease, Qin prophage; toxin-antitoxin (TA) pair RelEB, RelE inhibitor of translation cleaves mRNA in A site; binds to its antitoxin RelB and to ribosomes; co-repressor of relB operon transcription; stress-induced
  # bp Upstream # bp Downstream
MW: 11225.22 ---------95 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1645346
Left Intergenic Region

Name: hokD_relE

Length: 71 bp gap

Orientation: Codirectional-

Left_end: 1645275

Right_end: 1645345

Centisome: 35.45

Genomic Address
Counterclockwise
Minute or Centisome (%) = 35.45
Right End: 1645633
Right Intergenic Region

Name: relE_relB

Length: 1 bp overlap

Orientation: Codirectional-

Left_end: 1645633

Right_end: 1645633

Centisome: 35.45

Overproduction of RelE has been shown to increase persistence. Overexpression causes filamentous biofilm formation. Overexpression also reported to inhibit growth (Brown, 2003). Degraded by Lon protease.

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BamHI EcoRI HindIII