GenePage for the rsfS gene of Escherichia coli K-12

Primary Gene Name: rsfS
EcoGene Accession Number: EG11255
K-12 Gene Accession Number: ECK0630
MG1655 Gene Identifier: b0637
Gene Name Mnemonic: Ribosomal Silencing Factor, Starvation
Alternate Gene Symbols: rsfA; slm3; ybeB
Description: Ribosomal silencing factor
  # bp Upstream # bp Downstream
MW: 11582.23 ---------105 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 668719
Left Intergenic Region

Name: rlmH_rsfS

Length: 3 bp gap

Orientation: Codirectional-

Left_end: 668716

Right_end: 668718

Centisome: 14.41

Genomic Address
Minute or Centisome (%) = 14.41
Right End: 669036
Right Intergenic Region

Name: rsfS_cobC

Length: 259 bp gap

Orientation: Codirectional-

Left_end: 669037

Right_end: 669295

Centisome: 14.41

RsfS(YbeB) binds to ribosomal protein L14 and impairs ribosomal subunit joining during stationary phase and nutrient shift-down (Häuser, 2012). RsfS(YbeB) is homologous to the iojap pattern-striping gene of maize; DUF143 family. rsfS(ybeB) is a non-essential gene as shown by the tolerance of an insertion; the polar slm3 insertion is a synthetic lethal with minCD and causes a wide-cell phenotype in min+ cells; the rsfS(ybeB) phenotypes were attributed to reduced expression of downstream genes mrdA(pbpA) and/or mrdB(rodA), not rsfS(ybeB) itself, as shown with complementing plasmids (Bernhardt, 2004). The published gene name rsfA is changed to rsfS to avoid conflicts with different genes named rsfA earlier (P. Uetz, personal communication). RsfS(YbeB) is a ribosome-associated protein (Jiang, 2007).

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