GenePage for the nrdR gene of Escherichia coli K-12

Primary Gene Name: nrdR
EcoGene Accession Number: EG11320
K-12 Gene Accession Number: ECK0407
MG1655 Gene Identifier: b0413
Gene Name Mnemonic: Nucleotide reductase
Alternate Gene Symbols: ribX; ybaD
Description: Nrd regulon repressor
  # bp Upstream # bp Downstream
MW: 17228.89 ---------149 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 433002
Left Intergenic Region

Name: yajI_nrdR

Length: 150 bp gap

Orientation: Divergent

Left_end: 432852

Right_end: 433001

Centisome: 9.33

Genomic Address
Clockwise
Minute or Centisome (%) = 9.33
Right End: 433451
Right Intergenic Region

Name: nrdR_ribD

Length: 3 bp gap

Orientation: Codirectional+

Left_end: 433452

Right_end: 433454

Centisome: 9.34

NrdR has been shown to regulate all three Nrd systems and to bind to the predicted NrdR binding sites (Torrents, 2007). NrdR is homologous to S. coelicolor NrdR (Borovok, 2004). NrdR binding sites have been predicted for the nrdAB, nrdDG, and nrdHIEF operons (Rodionova, 2005). This corresponds to putative TF Binding Site Cluster E581 for nrdD and nrdA (Qin, 2003). Binds TrxA (Kumar, 2004). nrdR is the first gene in the putative nrdR-ribDE-nusB operon. NrdR is an ATP-cone domain protein.

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BamHI EcoRI HindIII