GenePage for the nhaB gene of Escherichia coli K-12

Primary Gene Name: nhaB
EcoGene Accession Number: EG11392
K-12 Gene Accession Number: ECK1174
MG1655 Gene Identifier: b1186
Gene Name Mnemonic: Na+/H+ antiporter
Alternate Gene Symbols: None
Description: Na+/H+ antiporter 2, weakly pH-dependent; helps regulate intracellular pH and extrude lithium
  # bp Upstream # bp Downstream
MW: 56728.41 ---------513 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1233176
Left Intergenic Region

Name: dsbB_nhaB

Length: 145 bp gap

Orientation: Codirectional-

Left_end: 1233031

Right_end: 1233175

Centisome: 26.56

Genomic Address
Counterclockwise
Minute or Centisome (%) = 26.57
Right End: 1234717
Right Intergenic Region

Name: nhaB_fadR

Length: 220 bp gap

Orientation: Divergent

Left_end: 1234718

Right_end: 1234937

Centisome: 26.60

NhaB, but not NhaA, is inhibited by the diuretic drugs amiloride and harmaline. IT (Ion Transporter) superfamily (Prakash, 2003). ST(3) structural class based on hydropathy profile (Lolkema, 2003).

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BamHI EcoRI HindIII