GenePage for the nrdD gene of Escherichia coli K-12

Primary Gene Name: nrdD
EcoGene Accession Number: EG11417
K-12 Gene Accession Number: ECK4233
MG1655 Gene Identifier: b4238
Gene Name Mnemonic: Nucleotide reductase
Alternate Gene Symbols: None
Description: Ribonucleoside-triphosphate reductase; class III anaerobic ribonucleotide reductase
  # bp Upstream # bp Downstream
Verified Start MW: 80022.56 ---------712 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4460522
Left Intergenic Region

Name: nrdG_nrdD

Length: 157 bp gap

Orientation: Codirectional-

Left_end: 4460365

Right_end: 4460521

Centisome: 96.09

Genomic Address
Counterclockwise
Minute or Centisome (%) = 96.10
Right End: 4462660
Right Intergenic Region

Name: nrdD_treC

Length: 393 bp gap

Orientation: Codirectional-

Left_end: 4462661

Right_end: 4463053

Centisome: 96.14

Activated NrdD is predicted to be cleaved by oxygen at the Gly681 radical, dropping the last 31 aa. Requires AdoMet for oxidation of the iron-sulfur center and glycine radical formation. FNR regulon. Binds TrxA (Kumar, 2004).

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BamHI EcoRI HindIII