GenePage for the hemE gene of Escherichia coli K-12

Primary Gene Name: hemE
EcoGene Accession Number: EG11543
K-12 Gene Accession Number: ECK3989
MG1655 Gene Identifier: b3997
Gene Name Mnemonic: Hemin
Alternate Gene Symbols: hemC
Description: Uroporphyrinogen decarboxylase
  # bp Upstream # bp Downstream
MW: 39248.12 ---------354 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4197716
Left Intergenic Region

Name: nudC_hemE

Length: 39 bp gap

Orientation: Codirectional+

Left_end: 4197677

Right_end: 4197715

Centisome: 90.43

Genomic Address
Clockwise
Minute or Centisome (%) = 90.44
Right End: 4198780
Right Intergenic Region

Name: hemE_nfi

Length: 9 bp gap

Orientation: Codirectional+

Left_end: 4198781

Right_end: 4198789

Centisome: 90.46

hemE mutants require media supplemented with 5-aminolevulinic acid (Sasarman, 1975). The hemE mutants in the Keio collection have been shown to harbor an intact copy of hemE in addition to the deletion allele (Yamamoto, 2009). The merodiploid hemE duplication in the Keio mutants strains probably compensates for the lack of supplemental 5-aminolevulinic acid.

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BamHI EcoRI HindIII