GenePage for the psuK gene of Escherichia coli K-12

Primary Gene Name: psuK
EcoGene Accession Number: EG11646
K-12 Gene Accession Number: ECK2159
MG1655 Gene Identifier: b2166
Gene Name Mnemonic: PSeudoUridine
Alternate Gene Symbols: pscK; yeiC
Description: Pseudouridine kinase; enzyme; pseudouridine utilization
  # bp Upstream # bp Downstream
MW: 33572.97 ---------313 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2258355
Left Intergenic Region

Name: psuG_psuK

Length: 13 bp overlap

Orientation: Codirectional-

Left_end: 2258355

Right_end: 2258367

Centisome: 48.65

Genomic Address
Counterclockwise
Minute or Centisome (%) = 48.65
Right End: 2259296
Right Intergenic Region

Name: psuK_fruA

Length: 422 bp gap

Orientation: Codirectional-

Left_end: 2259297

Right_end: 2259718

Centisome: 48.67

PsuK was characterized as the pseudouridine kinase required for pseudouridine utilization in E. coli UT189 (Preumont, 2008; Solomon, 1971). Mono-, di-, and triphosphates of pseudouridine have been identified in E. coli extracts (Ginsberg, 1968). psuKGT are not to be confused with mutations previously labeled psu before they were mapped to ORFs, namely (1) the psu polarity suppressor mutations that were found to map the the rho gene encoding the Rho protein, and (2) the pleiotropic suppressor psu mutations (Ephrati-Elizur, 1993) that have never been mapped to an ORF.

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BamHI EcoRI HindIII