GenePage for the setC gene of Escherichia coli K-12

Primary Gene Name: setC
EcoGene Accession Number: EG11687
K-12 Gene Accession Number: ECK3649
MG1655 Gene Identifier: b3659
Gene Name Mnemonic: Sugar efflux transporter
Alternate Gene Symbols: yicK
Description: Putative arabinose efflux transporter
  # bp Upstream # bp Downstream
MW: 43493.35 ---------394 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3836953
Left Intergenic Region

Name: yicT_setC

Length: 396 bp gap

Orientation: Codirectional+

Left_end: 3836557

Right_end: 3836952

Centisome: 82.65

Genomic Address
Clockwise
Minute or Centisome (%) = 82.66
Right End: 3838137
Right Intergenic Region

Name: setC_yicL

Length: 110 bp gap

Orientation: Codirectional+

Left_end: 3838138

Right_end: 3838247

Centisome: 82.69

SetC is a putative arabinose efflux transporter because a setC mutant has an increased intracellular concentration of arabinose but not xylose; in addition overexpression of SetC reduced the intracellular concentration of arabinose but not xylose; other sugars were not tested (Koita, 2012). SetC is predicted to be a sugar efflux transporter because it is a paralog of SetA and SetB. Major Facilitator Superfamily (MFS).

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BamHI EcoRI HindIII