GenePage for the cbrC gene of Escherichia coli K-12

Primary Gene Name: cbrC
EcoGene Accession Number: EG11727
K-12 Gene Accession Number: ECK3710
MG1655 Gene Identifier: b3717
Gene Name Mnemonic: CreB-regulated
Alternate Gene Symbols: yieJ
Description: Required for colicin E2 tolerance; UPF0167 family
  # bp Upstream # bp Downstream
MW: 22485.00 ---------195 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3898022
Left Intergenic Region

Name: cbrB_cbrC

Length: 48 bp gap

Orientation: Codirectional+

Left_end: 3897974

Right_end: 3898021

Centisome: 83.98

Genomic Address
Clockwise
Minute or Centisome (%) = 83.98
Right End: 3898609
Right Intergenic Region

Name: cbrC_yieK

Length: 61 bp gap

Orientation: Convergent

Left_end: 3898610

Right_end: 3898670

Centisome: 83.99

A cbrC(yieJ) mutant is hypersensitive to colicin E2; overproduction of CbrC(YieJ) increases colicin E2 tolerance (Cariss, 2010). CbrC(YieJ) has been predicted to have thiol-disulfide oxidoreductase activity similar to that of the glutaredoxin/thioredoxin family (Fetrow, 1998).

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BamHI EcoRI HindIII