GenePage for the yihY gene of Escherichia coli K-12

Primary Gene Name: yihY
EcoGene Accession Number: EG11851
K-12 Gene Accession Number: ECK3879
MG1655 Gene Identifier: b3886
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: rbn
Description: BrkB family putative transporter, inner membrane protein; function unknown
  # bp Upstream # bp Downstream
MW: 32838.91 ---------290 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4076146
Left Intergenic Region

Name: yihX_yihY

Length: 7 bp overlap

Orientation: Codirectional+

Left_end: 4076146

Right_end: 4076152

Centisome: 87.82

Genomic Address
Clockwise
Minute or Centisome (%) = 87.82
Right End: 4077018
Right Intergenic Region

Name: yihY_dtd

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 4077015

Right_end: 4077018

Centisome: 87.84

yihY is no longer thought to be the structural gene for RNase BN. The structural gene for RNase BN has been identified: the elaC gene has been renamed as rbn. yihY and yhjD are distant paralogs; YhjD is a putative lipid exporter. YihY(Rbn) has been shown to be an inner membrane protein that has six predicted TM regions with its C-terminus in the cytoplasm (Daley, 2005). YihY and YhjD belong to the B. pertussis virulence factor BrkB family (PF03631), formerly known as the UPF0761 family, although they have not been shown to be virulence factors in E. coli (Fernandez, 1994).

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BamHI EcoRI HindIII