GenePage for the psuG gene of Escherichia coli K-12

Primary Gene Name: psuG
EcoGene Accession Number: EG12033
K-12 Gene Accession Number: ECK2158
MG1655 Gene Identifier: b2165
Gene Name Mnemonic: PSeudoUridine
Alternate Gene Symbols: pscG; yeiN
Description: Pseudouridine 5'-phosphate glycosidase; pseudouridine utilization
  # bp Upstream # bp Downstream
MW: 32909.90 ---------312 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2257429
Left Intergenic Region

Name: psuT_psuG

Length: 93 bp gap

Orientation: Codirectional-

Left_end: 2257336

Right_end: 2257428

Centisome: 48.63

Genomic Address
Counterclockwise
Minute or Centisome (%) = 48.63
Right End: 2258367
Right Intergenic Region

Name: psuG_psuK

Length: 13 bp overlap

Orientation: Codirectional-

Left_end: 2258355

Right_end: 2258367

Centisome: 48.65

PsuG was characterized in E. coli UT189 (Preumont, 2008). PsuG also catalyzes the reverse reaction, of no known physiological significance, that was probably the enzyme previously described as a pseudouridylate synthetase (synthase) whose activity was correlated with pseudouridine utilization in various strains of E. coli and that was found to be sensitive to catabolite repression (Preumont, 2008; Solomon, 1971; Breitman, 1970). psuKGT are not to be confused with mutations previously labeled psu before they were mapped to ORFs, namely (1) the psu polarity suppressor mutations that were found to map the the rho gene encoding the Rho protein, and (2) the pleiotropic suppressor psu mutations (Ephrati-Elizur, 1993) that have never been mapped to an ORF.

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BamHI EcoRI HindIII