GenePage for the ccmE gene of Escherichia coli K-12

Primary Gene Name: ccmE
EcoGene Accession Number: EG12055
K-12 Gene Accession Number: ECK2189
MG1655 Gene Identifier: b2197
Gene Name Mnemonic: Cytochrome c maturation
Alternate Gene Symbols: yejS
Description: Heme chaperone, membrane-anchored, periplasmic
  # bp Upstream # bp Downstream
Verified Start MW: 17698.32 ---------159 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2294901
Left Intergenic Region

Name: ccmF_ccmE

Length: 4 bp overlap

Orientation: Codirectional-

Left_end: 2294901

Right_end: 2294904

Centisome: 49.44

Genomic Address
Counterclockwise
Minute or Centisome (%) = 49.44
Right End: 2295380
Right Intergenic Region

Name: ccmE_ccmD

Length: 4 bp overlap

Orientation: Codirectional-

Left_end: 2295377

Right_end: 2295380

Centisome: 49.45

CcmE makes a transient covalent linkage to heme at His-130 and then transfers heme to apocytochrome C in the presence of CcmFGH. Overexpression causes abnormal biofilm architecture. CcmE has a 29 aa signal anchor.

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BamHI EcoRI HindIII