GenePage for the mqo gene of Escherichia coli K-12

Primary Gene Name: mqo
EcoGene Accession Number: EG12069
K-12 Gene Accession Number: ECK2202
MG1655 Gene Identifier: b2210
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: yojH
Description: Malate oxidoreductase; possibly previously described FAD-dependent phospholipid-activated malate oxidase
  # bp Upstream # bp Downstream
MW: 60229.62 ---------548 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2305108
Left Intergenic Region

Name: eco_mqo

Length: 714 bp gap

Orientation: Convergent

Left_end: 2304394

Right_end: 2305107

Centisome: 49.65

Genomic Address
Counterclockwise
Minute or Centisome (%) = 49.66
Right End: 2306754
Right Intergenic Region

Name: mqo_yojI

Length: 217 bp gap

Orientation: Codirectional-

Left_end: 2306755

Right_end: 2306971

Centisome: 49.70

MQO activity is regulated by ArcA-ArcB regulatory system, carbon catabolite and growth phase (expressed in exponential phase with rapid degredation in stationary phase). Growth on pyruvate and acetate media resulted in high MQO activity while glucose media resulted in low activity, however, elevated MQO activity on glucose media in delta-arcA cells has been reported. Over expression of mqo results in depressed growth rates; deletion of mqo is reported to have no phenotype. Binds TrxA (Kumar, 2004).

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BamHI EcoRI HindIII