GenePage for the yojI gene of Escherichia coli K-12

Primary Gene Name: yojI
EcoGene Accession Number: EG12070
K-12 Gene Accession Number: ECK2203
MG1655 Gene Identifier: b2211
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: yojJ
Description: Microcin J25 efflux ABC transporter permease/ATPase; TolC-dependent
  # bp Upstream # bp Downstream
MW: 61552.80 ---------547 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2306972
Left Intergenic Region

Name: mqo_yojI

Length: 217 bp gap

Orientation: Codirectional-

Left_end: 2306755

Right_end: 2306971

Centisome: 49.70

Genomic Address
Counterclockwise
Minute or Centisome (%) = 49.70
Right End: 2308615
Right Intergenic Region

Name: yojI_alkB

Length: 75 bp gap

Orientation: Codirectional-

Left_end: 2308616

Right_end: 2308690

Centisome: 49.74

Overexpressed YojI confers Microcin J25 resistance and a yojI mutation confers Microcin J25 sensitivity. YojI is homologous to ABC-type transporter permease and ATP-binding components. No other overexpression resistance was found among 26 inhibitors tested. yojI is positively regulated by ppGpp resulting in microcin J25 resistance (Pomares, 2008).

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BamHI EcoRI HindIII