GenePage for the iscA gene of Escherichia coli K-12

Primary Gene Name: iscA
EcoGene Accession Number: EG12132
K-12 Gene Accession Number: ECK2525
MG1655 Gene Identifier: b2528
Gene Name Mnemonic: Iron-sulfur cluster
Alternate Gene Symbols: yfhF
Description: Recruit and deliver Fe for Fe-S cluster assembly in IscU; possibly an alternative scaffold for Fe-S cluster assembly
  # bp Upstream # bp Downstream
MW: 11556.05 ---------107 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2659563
Left Intergenic Region

Name: hscB_iscA

Length: 95 bp gap

Orientation: Codirectional-

Left_end: 2659468

Right_end: 2659562

Centisome: 57.30

Genomic Address
Counterclockwise
Minute or Centisome (%) = 57.30
Right End: 2659886
Right Intergenic Region

Name: iscA_iscU

Length: 16 bp gap

Orientation: Codirectional-

Left_end: 2659887

Right_end: 2659902

Centisome: 57.30

Either IscA or SufA are required for the proper assembly of 4Fe-4S clusters but not 2Fe-2S clusters (Tan, 2009). iscA, sufA, and erpA are paralogs; nfuA is a possible HT gene with an N-terminal domain homologous to sufA and an additional thioredoxin-like C-terminal domain.

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BamHI EcoRI HindIII