GenePage for the sgbE gene of Escherichia coli K-12

Primary Gene Name: sgbE
EcoGene Accession Number: EG12287
K-12 Gene Accession Number: ECK3572
MG1655 Gene Identifier: b3583
Gene Name Mnemonic: Sugar
Alternate Gene Symbols: yiaS
Description: L-ribulose 5-phosphate 4-epimerase; required for the aerobic utilization of L-ascorbate but not for fermentation; L-xylulose catabolism
  # bp Upstream # bp Downstream
MW: 25560.87 ---------231 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3750086
Left Intergenic Region

Name: sgbU_sgbE

Length: 7 bp overlap

Orientation: Codirectional+

Left_end: 3750086

Right_end: 3750092

Centisome: 80.79

Genomic Address
Clockwise
Minute or Centisome (%) = 80.79
Right End: 3750781
Right Intergenic Region

Name: sgbE_ysaC

Length: 31 bp gap

Orientation: Convergent

Left_end: 3750782

Right_end: 3750812

Centisome: 80.81

SgbE(YiaS) is possibly involved in the utilization of 2,3-diketo-L-gulonate, which can be formed by the hydrolysis of dehydroascorbate (Yew, 2002). A mutation in sbgE(yiaS) did not block xylulose catabolism formed from exogenous lyxose because lyxose induces the ara operon and AraD and SgbE(YibS) are isofunctional; a clone of either araD or sgbE(yiaS) can correct the xylulose catabolism defect of a double mutant; if the real inducer of sbgE(yiaS) operon does not induce the ara operon, then SbgE(YiaS) function would be required under normal operon induction conditions (IbaƱez, 2000).

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BamHI EcoRI HindIII