GenePage for the cueO gene of Escherichia coli K-12

Primary Gene Name: cueO
EcoGene Accession Number: EG12318
K-12 Gene Accession Number: ECK0122
MG1655 Gene Identifier: b0123
Gene Name Mnemonic: Cu efflux oxidase
Alternate Gene Symbols: cuiD(S.t.); yacK
Description: Multicopper oxidase (laccase), confers copper tolerance; oxidizes model substrate dimethoxyphenol; in vitro ferroxidase and phenoloxidase activities; regulated by copper-responsive CueR activator
  # bp Upstream # bp Downstream
Verified Start MW: 56556.15 ---------516 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 137083
Left Intergenic Region

Name: yacC_cueO

Length: 165 bp gap

Orientation: Divergent

Left_end: 136918

Right_end: 137082

Centisome: 2.95

Genomic Address
Clockwise
Minute or Centisome (%) = 2.95
Right End: 138633
Right Intergenic Region

Name: cueO_gcd

Length: 201 bp gap

Orientation: Convergent

Left_end: 138634

Right_end: 138834

Centisome: 2.99

CueO was the only copper-binding protein found using Cu-MIRAGE (Sevcenco, 2009; Sevcenco, 2012). Verified Tat substrate: CueO has a Tat/Sec (Class II) 28 aa signal peptide (Tullman-Ercek, 2007).

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BamHI EcoRI HindIII