GenePage for the clcA gene of Escherichia coli K-12

Primary Gene Name: clcA
EcoGene Accession Number: EG12331
K-12 Gene Accession Number: ECK0154
MG1655 Gene Identifier: b0155
Gene Name Mnemonic: Chloride carrier/channel
Alternate Gene Symbols: eriC; yadQ
Description: H(+)/Cl(-) exchange transporter; involved in the extreme acid response
  # bp Upstream # bp Downstream
MW: 50348.72 ---------473 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 175107
Left Intergenic Region

Name: hemL_clcA

Length: 224 bp gap

Orientation: Divergent

Left_end: 174883

Right_end: 175106

Centisome: 3.77

Genomic Address
Clockwise
Minute or Centisome (%) = 3.77
Right End: 176528
Right Intergenic Region

Name: clcA_erpA

Length: 81 bp gap

Orientation: Codirectional+

Left_end: 176529

Right_end: 176609

Centisome: 3.80

ClcA and ClcB encode redundant chloride transporters; single mutants have no phenotype. ClcA, ClcB and YfeO belong to the Pfam PF00654 Voltage_CLC family of ion channels and ion exchange transporters. Although the PDB structure 4FG6 is derived from E. coli strain S. sonnei Ss046, its protein sequence is identical to the K-12 allele.

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BamHI EcoRI HindIII