GenePage for the fliY gene of Escherichia coli K-12

Primary Gene Name: fliY
EcoGene Accession Number: EG12680
K-12 Gene Accession Number: ECK1919
MG1655 Gene Identifier: b1920
Gene Name Mnemonic: Flagella
Alternate Gene Symbols: yzzR
Description: Cystine-binding protein, periplasmic; part of a L-cysteine/L-cystine shuttle system confering hydrogen peroxide resistance; not required for motility; may regulate FliA (sigma 28)
  # bp Upstream # bp Downstream
Verified Start MW: 29039.19 ---------266 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1999585
Left Intergenic Region

Name: dcyD_fliY

Length: 104 bp gap

Orientation: Codirectional-

Left_end: 1999481

Right_end: 1999584

Centisome: 43.08

Genomic Address
Counterclockwise
Minute or Centisome (%) = 43.08
Right End: 2000385
Right Intergenic Region

Name: fliY_fliZ

Length: 87 bp gap

Orientation: Codirectional-

Left_end: 2000386

Right_end: 2000472

Centisome: 43.10

EamA(YdeD) and FliY constitute a L-cysteine/L-cystine shuttle system confering hydrogen peroxide resistance; FliY and an unknown membrane import permease partner mediate the import of cystine, oxidized cysteine, from the periplasm to the cytoplasm to regenerate cysteine; eamA(ydeD), eamB(yfiK) and fliY are induced by hydrogen peroxide and cysteine (Ohtsu, 2010). FliY, YecC and YecS may constitute an ABC transport system for the import of L-cystine.

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BamHI EcoRI HindIII