GenePage for the yhcH gene of Escherichia coli K-12

Primary Gene Name: yhcH
EcoGene Accession Number: EG12814
K-12 Gene Accession Number: ECK3210
MG1655 Gene Identifier: b3221
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: None
Description: DUF386 family protein, cupin superfamily; required for swarming phenotype
  # bp Upstream # bp Downstream
MW: 17037.68 ---------154 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3369014
Left Intergenic Region

Name: yhcG_yhcH

Length: 59 bp gap

Orientation: Convergent

Left_end: 3368955

Right_end: 3369013

Centisome: 72.58

Genomic Address
Counterclockwise
Minute or Centisome (%) = 72.58
Right End: 3369478
Right Intergenic Region

Name: yhcH_nanK

Length: 4 bp overlap

Orientation: Codirectional-

Left_end: 3369475

Right_end: 3369478

Centisome: 72.59

EbgC is a distant homolog of YiaL, YhcH and TabA(YjgK), all four match PF04074; although homologous to the beta subunit of the EbgAC evolved beta-galactosidase, no potential EbgA-like alpha subunit partners are apparent for the other three DUF386 family proteins. otherPDB (H. influenzae): 1JOP, 1S4C. The H. influenzae structures reveals a likely active site, proposed to be a copper-dependent sugar isomerase. yhcH is the last gene in the nanATEK-yhcH operon, but is not required for growth on sialic acid (Plumbridge, 1999).

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BamHI EcoRI HindIII