GenePage for the yggT gene of Escherichia coli K-12

Primary Gene Name: yggT
EcoGene Accession Number: EG12980
K-12 Gene Accession Number: ECK2947
MG1655 Gene Identifier: b2952
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: None
Description: Predicted inner membrane protein; compensates for loss in K+ uptake
  # bp Upstream # bp Downstream
MW: 21167.11 ---------188 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3095820
Left Intergenic Region

Name: yggS_yggT

Length: 17 bp gap

Orientation: Codirectional+

Left_end: 3095803

Right_end: 3095819

Centisome: 66.70

Genomic Address
Clockwise
Minute or Centisome (%) = 66.70
Right End: 3096386
Right Intergenic Region

Name: yggT_yggU

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 3096383

Right_end: 3096386

Centisome: 66.71

Although V. alginolyticus FkuAB stimulates K+ uptake, YggT appears to rescue TK420 (lacking K+ uptake systems Trk, Kup and Kdp) without increasing K+ uptake, through an unknown mechanism (Ito, 2009). Chromosomal yggT is probably not expressed since low level plasmid-based yggT expression was required for the rescue of TK420 (lacking K+ uptake systems Trk, Kup and Kdp) (Ito, 2009). YggS is not required to help YggT in the K+ uptake rescue of TK420 (lacking K+ uptake systems Trk, Kup and Kdp) (Ito, 2009). V. alginolyticus FkuB, a YggT homolog, confers K+ uptake (with FkuA, a YggS homolog) on E. coli TK420 (lacking K+ uptake systems Trk, Kup and Kdp) (Nakamura, 1996). YggT is the prototype for a family of proteins of unknown function (Pfam PF02325); YggT is comprised of two tandem YggT motifs.

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BamHI EcoRI HindIII