GenePage for the emrK gene of Escherichia coli K-12

Primary Gene Name: emrK
EcoGene Accession Number: EG13282
K-12 Gene Accession Number: ECK2364
MG1655 Gene Identifier: b2368
Gene Name Mnemonic: Efflux-multidrug resistance
Alternate Gene Symbols: None
Description: EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein; overexpression resistance to deoxycholate; signal anchored membrane protein
  # bp Upstream # bp Downstream
MW: 42585.45 ---------387 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2482176
Left Intergenic Region

Name: emrY_emrK

Length: 1 bp overlap

Orientation: Codirectional-

Left_end: 2482176

Right_end: 2482176

Centisome: 53.48

Genomic Address
Counterclockwise
Minute or Centisome (%) = 53.48
Right End: 2483339
Right Intergenic Region

Name: emrK_evgA

Length: 415 bp gap

Orientation: Divergent

Left_end: 2483340

Right_end: 2483754

Centisome: 53.50

Mutations in emrK have a hyperlethality phenotype when cells are stressed; EmrK is a protein that reduces the lethal effects of stress (Han, 2010). EvgAS regulon.

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BamHI EcoRI HindIII