GenePage for the csgD gene of Escherichia coli K-12

Primary Gene Name: csgD
EcoGene Accession Number: EG13410
K-12 Gene Accession Number: ECK1026
MG1655 Gene Identifier: b1040
Gene Name Mnemonic: Curlin sigma S-dependent growth
Alternate Gene Symbols: agfD(S.t.)
Description: Transcriptional activator for csgBA and other genes
  # bp Upstream # bp Downstream
MW: 24935.47 ---------216 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1102546
Left Intergenic Region

Name: csgE_csgD

Length: 4 bp gap

Orientation: Codirectional-

Left_end: 1102542

Right_end: 1102545

Centisome: 23.75

Genomic Address
Counterclockwise
Minute or Centisome (%) = 23.75
Right End: 1103196
Right Intergenic Region

Name: csgD_csgB

Length: 754 bp gap

Orientation: Divergent

Left_end: 1103197

Right_end: 1103950

Centisome: 23.77

Hfq-dependent omrA and omrB sRNAs downregulate curli gene activator CsgD post-transcriptionally and repress curli formation (Holmqvist, 2010). CsgD (AgfD) has also been characterized in Salmonella. CsgD increases expression of glyA. csgD insertions eliminate RpoS-dependent transcription from the csgBA promoter. Cytoplasmic membrane-associated.

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BamHI EcoRI HindIII