GenePage for the dmlA gene of Escherichia coli K-12

Primary Gene Name: dmlA
EcoGene Accession Number: EG13507
K-12 Gene Accession Number: ECK1798
MG1655 Gene Identifier: b1800
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: yeaU
Description: D-malate oxidase, NAD(+)-dependent
  # bp Upstream # bp Downstream
MW: 40314.93 ---------361 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1881912
Left Intergenic Region

Name: dmlR_dmlA

Length: 102 bp gap

Orientation: Divergent

Left_end: 1881810

Right_end: 1881911

Centisome: 40.54

Genomic Address
Clockwise
Minute or Centisome (%) = 40.54
Right End: 1882997
Right Intergenic Region

Name: dmlA_yeaV

Length: 190 bp gap

Orientation: Codirectional+

Left_end: 1882998

Right_end: 1883187

Centisome: 40.57

DmlA(YeaU) is 77% identical to a characterized tartrate dehydrogenase from Pseudomonas putida (SP:Q51945); this P. putida enzyme also has D-malate oxidase activity (Karsten, 2002). The D-malate oxidase activity of YeaU has been confirmed (Reed, 2006), but the probable tartrate dehydrogenase activity has not been tested. Mutations in yeaT or yeaU block growth on D-malate (Reed, 2006). After four hours of Zn(II) stress, protein levels increased (Easton, 2006).

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BamHI EcoRI HindIII