GenePage for the nemA gene of Escherichia coli K-12

Primary Gene Name: nemA
EcoGene Accession Number: EG13546
K-12 Gene Accession Number: ECK1646
MG1655 Gene Identifier: b1650
Gene Name Mnemonic: N-Ethylmaleimide
Alternate Gene Symbols: ydhN
Description: Chromate reductase, quinone reductase, FMN-linked; N-Ethylmaleimide reductase; old yellow enzyme
  # bp Upstream # bp Downstream
MW: 39516.41 ---------365 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1726659
Left Intergenic Region

Name: nemR_nemA

Length: 36 bp gap

Orientation: Codirectional+

Left_end: 1726623

Right_end: 1726658

Centisome: 37.20

Genomic Address
Clockwise
Minute or Centisome (%) = 37.20
Right End: 1727756
Right Intergenic Region

Name: nemA_gloA

Length: 80 bp gap

Orientation: Codirectional+

Left_end: 1727757

Right_end: 1727836

Centisome: 37.22

NemA is a chromate reductase (Robins, 2013). nemA is part of the nemRA-gloA operon involved in electrophile detoxification; NemA can reduce quinones and other electrophiles (Lee, 2013). NemA is the "old yellow enzyme" (OYE) of E. coli (Williams, 2002). nemR mutants suppress the putative malonic semialdehyde reductase defects of rutE or ydfG mutants, presuambly by overproducing NemA (Kim, 2010). The original characterization of NemA called it a cis-enoyl-CoA reductase involved in the beta-oxidation of fatty acids such as linoleic acid (Mizugaki, 1979).

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BamHI EcoRI HindIII