GenePage for the ykgF gene of Escherichia coli K-12

Primary Gene Name: ykgF
EcoGene Accession Number: EG13583
K-12 Gene Accession Number: ECK0306
MG1655 Gene Identifier: b0307
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: None
Description: Ferridoxin-like LutB family protein; predicted electron transport chain YkgEFG component; predicted lactate-related compound oxidative catabolism
  # bp Upstream # bp Downstream
MW: 53051.90 ---------475 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 322338
Left Intergenic Region

Name: ykgE_ykgF

Length: 10 bp gap

Orientation: Codirectional+

Left_end: 322328

Right_end: 322337

Centisome: 6.94

Genomic Address
Minute or Centisome (%) = 6.94
Right End: 323765
Right Intergenic Region

Name: ykgF_ykgG

Length: 8 bp overlap

Orientation: Codirectional+

Left_end: 323758

Right_end: 323765

Centisome: 6.98

YkgEFG is homologous to the B. subtilis LutABC oxidative lactate catabolism putative electron chain, but ykgEFG does not complement lutABC, perhaps indicating a lactate-related compound is catabolized by YkgEFG; a ykgF mutant is still able to utilize lactate, presumably utilizing LldPRD function (Chai, 2009). YkgF is comprised of a LutB family domain (Pfam PF02589), followed by a 4Fe-4S dicluster domain (PF13183) and a C-terminal DUF3390 domain (PF11870); the LutC family domain (Pfam PF02589) belongs to a 5-formyltetrahydrofolate cyclo-ligase-like superfamily (InterPro IPR024185) and a NagB/RpiA/CoA transferase-like structural clan (Superfamily SSF100950).

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