GenePage for the allA gene of Escherichia coli K-12

Primary Gene Name: allA
EcoGene Accession Number: EG13615
K-12 Gene Accession Number: ECK0498
MG1655 Gene Identifier: b0505
Gene Name Mnemonic: Allantoin
Alternate Gene Symbols: glxA2; ybbT
Description: Ureidoglycolate lyase, releasing urea
  # bp Upstream # bp Downstream
MW: 18169.55 ---------160 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 532451
Left Intergenic Region

Name: allS_allA

Length: 229 bp gap

Orientation: Divergent

Left_end: 532222

Right_end: 532450

Centisome: 11.47

Genomic Address
Clockwise
Minute or Centisome (%) = 11.47
Right End: 532933
Right Intergenic Region

Name: allA_allR

Length: 77 bp gap

Orientation: Codirectional+

Left_end: 532934

Right_end: 533010

Centisome: 11.48

Ureidoglycolate is converted to glyoxylate and urea by AllA, which is not required for allantoin catabolism (Cusa, 1999; Werner, 2010). The crystal structure of AllA from E. coli O157:H7 (PDB:1YQC) differs from K-12 at a single position, C51R (Raymond, 2005). The crystal structure of AllA from Shigella flexneri (PDB:1XSR) differs from K-12 at a single position, C51R. AllA has long been misannotated as ureidoglycolate hydrolase in many database entries and publications (Percudani, 2013).

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BamHI EcoRI HindIII