GenePage for the ybhR gene of Escherichia coli K-12

Primary Gene Name: ybhR
EcoGene Accession Number: EG13674
K-12 Gene Accession Number: ECK0781
MG1655 Gene Identifier: b0792
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: None
Description: Putative ABC transporter permease
  # bp Upstream # bp Downstream
MW: 41565.85 ---------368 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 825002
Left Intergenic Region

Name: ybhQ_ybhR

Length: 39 bp overlap

Orientation: Convergent

Left_end: 825002

Right_end: 825040

Centisome: 17.77

Genomic Address
Counterclockwise
Minute or Centisome (%) = 17.77
Right End: 826108
Right Intergenic Region

Name: ybhR_ybhS

Length: 10 bp gap

Orientation: Codirectional-

Left_end: 826109

Right_end: 826118

Centisome: 17.80

The putative ybiHybhGFSR operon encodes a predicted transcriptional regulator (YbiH) and four proteins of a predicted ABC-type transporter complex YbhGFSR, containing two ABC permease family members (YbhSR), a predicted ATP-binding cassette protein (YbhF), and a predicted membrane fusion protein (YbhG) usually associated with RND-type efflux pumps. No predicted periplasmic binding protein is associated with this predicted ABC transporter YbhGFSR, suggesting that it is an exporter, which is consistent with the presence of a membrane fusion protein (YbhG) allowing for export transit across the periplasm. YbhG (f332) was mistakenly predicted to be a periplasmic binding protein, leading to the mis-classification of YbhGFSR as a putative importer (Linton, 1998). YadH, YbhR, YbhS, YhhJ, and the RbbA C-terminal domain are paralogous ABC2-membrane permease family members (pfam01061/COG0842).

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BamHI EcoRI HindIII