GenePage for the ycaO gene of Escherichia coli K-12

Primary Gene Name: ycaO
EcoGene Accession Number: EG13699
K-12 Gene Accession Number: ECK0896
MG1655 Gene Identifier: b0905
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: None
Description: Ribosomal protein S12 methylthiotransferase accessory factor
  # bp Upstream # bp Downstream
MW: 65651.58 ---------586 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 954872
Left Intergenic Region

Name: focA_ycaO

Length: 405 bp gap

Orientation: Codirectional-

Left_end: 954467

Right_end: 954871

Centisome: 20.56

Genomic Address
Counterclockwise
Minute or Centisome (%) = 20.57
Right End: 956632
Right Intergenic Region

Name: ycaO_ycaP

Length: 129 bp gap

Orientation: Divergent

Left_end: 956633

Right_end: 956761

Centisome: 20.61

YcaO is required for the efficient in vivo RimO-dependent beta-methylthiolation of ribosomal protein S12 (RpsL) on Asp-89 (Strader, 2011). Overexpression causes filamentous biofilm formation and reduced motility. The YcaO domain protein BalhD is the catalytic subunit of the ATP-dependent cyclodehydratase BalhCD from Bacillus sp. Al Hakam involved in thiazole/oxazole-modified microcin (TOMM) biosynthesis (Dunbar, 2012). Member of UPF0142 family. DUF181 protein.

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BamHI EcoRI HindIII