GenePage for the gfcB gene of Escherichia coli K-12

Primary Gene Name: gfcB
EcoGene Accession Number: EG13731
K-12 Gene Accession Number: ECK0977
MG1655 Gene Identifier: b0986
Gene Name Mnemonic: Group 4 Capsule
Alternate Gene Symbols: ymcC
Description: Lipoprotein required to make O-antigen capsule; predicted outer membrane location
  # bp Upstream # bp Downstream
MW: 24267.58 ---------214 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1048688
Left Intergenic Region

Name: gfcC_gfcB

Length: 4 bp overlap

Orientation: Codirectional-

Left_end: 1048688

Right_end: 1048691

Centisome: 22.59

Genomic Address
Counterclockwise
Minute or Centisome (%) = 22.59
Right End: 1049332
Right Intergenic Region

Name: gfcB_gfcA

Length: 106 bp gap

Orientation: Codirectional-

Left_end: 1049333

Right_end: 1049438

Centisome: 22.61

E. coli K-12 does not produce O-antigen capsule polysaccharide because the cryptic gfcABCDE-etp-etk operon is silenced by IS1D in the promoter region (Peleg, 2005). GfcB is required for O-antigen capsule formation in enteropathogenic E. coli (EPEC) (Peleg, 2005). gfcB(ymcC) and yjbF are paralogs. The first 15 aa of GfcB are a type II signal peptide.

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII