GenePage for the pgrR gene of Escherichia coli K-12

Primary Gene Name: pgrR
EcoGene Accession Number: EG13923
K-12 Gene Accession Number: ECK1325
MG1655 Gene Identifier: b1328
Gene Name Mnemonic: Peptide glycan recycling regulator
Alternate Gene Symbols: ycjZ
Description: Murein peptide degradation regulator
  # bp Upstream # bp Downstream
MW: 33481.78 ---------299 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1391991
Left Intergenic Region

Name: ycjY_pgrR

Length: 137 bp gap

Orientation: Divergent

Left_end: 1391854

Right_end: 1391990

Centisome: 29.99

Genomic Address
Clockwise
Minute or Centisome (%) = 29.99
Right End: 1392890
Right Intergenic Region

Name: pgrR_mppA

Length: 336 bp gap

Orientation: Codirectional+

Left_end: 1392891

Right_end: 1393226

Centisome: 30.01

PgrR(YjcZ) is a global regulator involved in murein peptide degradation specifically acting as a transcriptional repressor for the downstream mppA gene and for the divergent ycjY-ymjD'-ymjC'-mpaA defective operon; PgrR is proposed to be involved in the switch decision to recycle or degrade murein peptides; additional genes at distal loci are also regulated by PgrR (Shimada, 2013). PgrR(YjcZ) is required for swarming motility. LysR family.

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BamHI EcoRI HindIII