GenePage for the rsxG gene of Escherichia coli K-12

Primary Gene Name: rsxG
EcoGene Accession Number: EG13937
K-12 Gene Accession Number: ECK1627
MG1655 Gene Identifier: b1631
Gene Name Mnemonic: Reducer of SoxR
Alternate Gene Symbols: rnfG(R.c.); ydgP
Description: SoxR iron-sulfur cluster reduction factor component; putative membrane protein of electron transport complex; probable ThiC reduction factor
  # bp Upstream # bp Downstream
MW: 21911.91 ---------206 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1710204
Left Intergenic Region

Name: rsxD_rsxG

Length: 3 bp gap

Orientation: Codirectional+

Left_end: 1710201

Right_end: 1710203

Centisome: 36.84

Genomic Address
Clockwise
Minute or Centisome (%) = 36.84
Right End: 1710824
Right Intergenic Region

Name: rsxG_rsxE

Length: 3 bp gap

Orientation: Codirectional+

Left_end: 1710825

Right_end: 1710827

Centisome: 36.86

ApbE is probably required for a covalent flavination of conserved residues Thr187 in RsxD and Thr174 in RsxG with FMN, which then are likely to be required for the reduction of the 4Fe-4S cluster in ThiC in addition to the known Rsx function to reduce the 2Fe-2S cluster in SoxR. ApbE of Vibrio harveyi is a flavin transferase required for the covalent flavinylation of NqrC, an RsxG homolog, with FMN at position Thr229 (Bertsova, 2013). Vibrio cholerae RnfD (RsxD homolog) and RnfG (RsxG homolog) are covalently FMN flavinylated at residues Thr187 and Thr175, respectively (Backiel, 2008). Vibrio alginolyticus NqrC (RsxG homolog) and NqrB (RsxD homolog) are covalently FMN flavinylated at residues Thr223 and Thr235, respectively (Hayashi, 2001).

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BamHI EcoRI HindIII