GenePage for the yfaP gene of Escherichia coli K-12

Primary Gene Name: yfaP
EcoGene Accession Number: EG14078
K-12 Gene Accession Number: ECK2218
MG1655 Gene Identifier: b2225
Gene Name Mnemonic: Systematic nomenclature
Alternate Gene Symbols: None
Description: DUF2135 family protein, function unknown; predicted host defense protein
  # bp Upstream # bp Downstream
MW: 28303.67 ---------258 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2327367
Left Intergenic Region

Name: atoB_yfaP

Length: 73 bp gap

Orientation: Convergent

Left_end: 2327294

Right_end: 2327366

Centisome: 50.14

Genomic Address
Counterclockwise
Minute or Centisome (%) = 50.14
Right End: 2328143
Right Intergenic Region

Name: yfaP_yfaQ

Length: 4 bp gap

Orientation: Codirectional-

Left_end: 2328144

Right_end: 2328147

Centisome: 50.16

yfaP is in the yfaATSQP operon encoding the variant bacterial alpha2-macroglobulin family protein YfaS, leading to a prediction that YfaT is also involved in host defenses, possibly in the extracellular environment (Budd, 2004). The first 19 aa of YfaP are predicted to be a type I signal peptide. YfaP belongs to the COG4676 family and has a ~45 aa DUF2135 domain near the C-terminus.

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BamHI EcoRI HindIII