GenePage for the gtrA gene of Escherichia coli K-12

Primary Gene Name: gtrA
EcoGene Accession Number: EG14131
K-12 Gene Accession Number: ECK2344
MG1655 Gene Identifier: b2350
Gene Name Mnemonic: Glucosyl transferase
Alternate Gene Symbols: yfdG
Description: Bactoprenol-linked glucose translocase, CPS-53/KpLE1 prophage; part of the GtrABS tripartite system for prophage seroconversion of type IV O antigen to serotype 4a
  # bp Upstream # bp Downstream
MW: 13225.75 ---------120 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2467855
Left Intergenic Region

Name: intS_gtrA

Length: 152 bp gap

Orientation: Codirectional+

Left_end: 2467703

Right_end: 2467854

Centisome: 53.16

Genomic Address
Clockwise
Minute or Centisome (%) = 53.17
Right End: 2468217
Right Intergenic Region

Name: gtrA_gtrB

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 2468214

Right_end: 2468217

Centisome: 53.18

GtrB transfers glucose from UDP-glucose to undecaprenyl pyrophosphate before translocation by GtrA. GtrAB are highly conserved and the K-12 genes have been shown to be functional in partial converting Shigella flexneri serotype Y strain SFL124 to serotype 4a in conjunction with the serotype-specific glucosyl transferase GtrS and fully functional group 7,8 seroconversion when paired with the GtrX group 7,8 serotype-specific glucosyl transferase, as assessed by serum-induced agglutination and SfV bactieriophage sensitivty (Adams, 2001).

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BamHI EcoRI HindIII